首都醫(yī)學(xué)科學(xué)創(chuàng)新中心（簡稱創(chuàng)新中心）是北京市新成立的具有獨立法人資格的新型研發(fā)機構(gòu)。創(chuàng)新中心以推動醫(yī)學(xué)科學(xué)發(fā)展、改善人類健康為目標(biāo)，開展生物醫(yī)學(xué)研究，致力于提升醫(yī)學(xué)科學(xué)創(chuàng)新與成果轉(zhuǎn)化能力，提高疾病診斷和治療水平。我們將匯聚世界高水平科學(xué)家，與首都醫(yī)學(xué)教育和科學(xué)研究優(yōu)質(zhì)資源緊密合作，打造多學(xué)科交叉融合的科研平臺，綜合自由探索、醫(yī)學(xué)目標(biāo)導(dǎo)向、有組織科研等途徑，實踐新型科研模式和體制機制，逐步推進(jìn)醫(yī)教研產(chǎn)的深度融合，培養(yǎng)適應(yīng)醫(yī)學(xué)科學(xué)創(chuàng)新發(fā)展的優(yōu)秀人才。
一、實驗室介紹
Yun實驗室團(tuán)隊以蠑螈為模型系統(tǒng)，致力于揭示器官再生的細(xì)胞與分子機制，解析演化差異對再生潛能的影響，并探索再生與衰老的深層關(guān)聯(lián)。我們采用兩種具有基因操作可行性的蠑螈模型——墨西哥鈍口螈（美西螈，Ambystoma mexicanum）和西班牙肋突螈（Pleurodeles waltl），這兩種生物以極強的再生能力和幾乎可以忽略的衰老特征而著稱。通過整合前沿遺傳學(xué)技術(shù)、細(xì)胞分子生物學(xué)方法、先進(jìn)成像系統(tǒng)、多組學(xué)分析與跨物種比較研究，我們致力于揭示再生與衰老的基本規(guī)律，推動基礎(chǔ)研究與治療應(yīng)用。
掃碼了解更多_二維碼（請點擊鏈接查看詳情）
我們提供國際化、創(chuàng)新性強且以科學(xué)為導(dǎo)向的科研環(huán)境。入選者將加入我們覆蓋德國、英國、美國的國際合作網(wǎng)絡(luò)，并有機會直接參與國際項目。實驗室隸屬于新成立的首都醫(yī)學(xué)科學(xué)創(chuàng)新中心的再生生物學(xué)與醫(yī)學(xué)研究所。
二、崗位信息
01、實驗室管理員
我們正在為新建實驗室招募一名技術(shù)嫻熟的科研管理人員。
1）崗位職責(zé)
1.設(shè)備、試劑及實驗室耗材的采購與管理；
2.庫存維護(hù)與檔案記錄；
3.常規(guī)設(shè)備維護(hù)及實驗室日常運營；
4.新成員實驗技術(shù)與設(shè)備操作培訓(xùn)；
5.協(xié)助動物實驗倫理審批及許可證辦理；
6.開展基礎(chǔ)分子/細(xì)胞生物學(xué)實驗、圖像采集與數(shù)據(jù)分析；
7.參與合作研究并獨立承擔(dān)課題。
2）任職要求
1.分子生物學(xué)、生物化學(xué)或相關(guān)專業(yè)學(xué)位；
2.具備實驗室管理經(jīng)驗；
3.熟練掌握以下分子生物學(xué)技術(shù)：
?基因克隆與編輯
?細(xì)胞培養(yǎng)
?顯微成像技術(shù)（共聚焦/立體熒光/光片顯微鏡等）
?組織處理（樣本制備、切片及染色技術(shù)，包括免疫組化IHC/IF、常規(guī)/HCR原位雜交）
4.有動物實驗與轉(zhuǎn)基因操作經(jīng)驗者優(yōu)先；
5.素質(zhì)要求：
?卓越的組織協(xié)調(diào)能力
?對細(xì)節(jié)的高度關(guān)注
?流利的英語口語與書面表達(dá)能力
02、分子生物學(xué)技術(shù)員
我們誠聘一名熟練掌握分子生物學(xué)技術(shù)的專業(yè)人員，共同探索再生與衰老的關(guān)聯(lián)機制。該職位需具備獨立開展研究及團(tuán)隊協(xié)作能力。
1）崗位職責(zé)
運用前沿分子生物學(xué)技術(shù)開展相關(guān)研究。
2）任職要求
1.扎實的分子生物學(xué)技術(shù)背景，包括：
?先進(jìn)基因編輯技術(shù)（如CRISPR/Cas-9系統(tǒng)）
?克隆技術(shù)
?mTol2或類似轉(zhuǎn)基因系統(tǒng)操作
?動物轉(zhuǎn)基因技術(shù)
?細(xì)胞培養(yǎng)
?組織處理技術(shù)（樣本制備、切片及染色，包括免疫組化IHC/IF和常規(guī)/HCR原位雜交）
2.有再生模型研究或動物手術(shù)經(jīng)驗者優(yōu)先；
3.素質(zhì)要求：
?細(xì)致嚴(yán)謹(jǐn)?shù)墓ぷ鲬B(tài)度
?流利的英語聽說讀寫能力
03、生物信息分析師
我們誠聘一名積極主動的生物信息學(xué)專業(yè)人員，共同探索再生與衰老的關(guān)聯(lián)機制。
1）崗位職責(zé)
1.設(shè)計并開展單細(xì)胞及群體水平的生物信息學(xué)分析，包括：
?轉(zhuǎn)錄組、表觀遺傳組（如DNA甲基化芯片、基因組數(shù)據(jù)）及蛋白質(zhì)組數(shù)據(jù)分析
?基于10XMultiome工作流程和Illumina測序平臺生成的mRNA測序數(shù)據(jù)分析
2.開展跨物種單細(xì)胞分析；
3.解析空間轉(zhuǎn)錄組數(shù)據(jù)；
4.參與科學(xué)假說提出、實驗設(shè)計、分析流程文檔編寫、研究匯報及論文撰寫；
5.為團(tuán)隊成員提供技術(shù)培訓(xùn)與指導(dǎo)；
6.協(xié)調(diào)獨立工作與團(tuán)隊協(xié)作。
2）任職要求
1.生物信息學(xué)或相關(guān)領(lǐng)域?qū)W位；
2.扎實的生物信息學(xué)理論基礎(chǔ)及實踐經(jīng)驗，尤其擅長：
?單細(xì)胞數(shù)據(jù)分析
?空間轉(zhuǎn)錄組學(xué)分析
3.必備流利的英語聽說讀寫能力；
4.有再生生物學(xué)、衰老研究或進(jìn)化生物學(xué)經(jīng)驗者優(yōu)先。
04、博士后
我們誠邀優(yōu)秀且富有科研熱情的博士后研究人員加入，共同探索再生與衰老的分子關(guān)聯(lián)機制。
1）任職要求
1.已獲得或即將獲得生物學(xué)、生物化學(xué)、計算生物學(xué)等相關(guān)專業(yè)博士學(xué)位；
2.具備突出的學(xué)術(shù)成果記錄；
3.流利的英語聽說讀寫能力；
4.具有再生生物學(xué)、衰老研究、發(fā)育生物學(xué)或進(jìn)化生物學(xué)背景者優(yōu)先；
5.具備以下技術(shù)經(jīng)驗者尤佳（滿足部分即可）：
?動物實驗操作
?組織培養(yǎng)技術(shù)
?生物信息學(xué)分析
?細(xì)胞與分子生物學(xué)實驗技術(shù)
三、福利待遇
1.根據(jù)應(yīng)聘者的工作經(jīng)驗和能力，提供具有市場競爭力的薪酬（詳情面談）；
2.享受五險一金、帶薪年假、體檢和補充醫(yī)療保險等；
3.支持個人職業(yè)發(fā)展，提供必要的工作相關(guān)專業(yè)培訓(xùn)。
四、申請方法
請將簡歷、研究興趣、3名推薦人的姓名和聯(lián)系方式以及其他證明研究能力的材料發(fā)送至max.yun@cimrbj.ac.cn，請【點擊下方“立即投遞/投遞簡歷”，即刻進(jìn)行職位報名】，并在郵件主題中注明申請人的姓名和具體職位。
聯(lián)系人：Max H.Yun
聯(lián)系地址：北京市豐臺區(qū)右安門外西頭條10號-首都醫(yī)學(xué)科學(xué)創(chuàng)新中心
本招聘長期有效，至招聘到合適人選為止。
ABOUT CIMR
Chinese Institutes for
Medical Research (CIMR) is a newly founded institution dedicated to fundamental
and translational medical research.The CIMR is located at the main campus of
the
ABOUT YUN LAB
The Yun group leverages salamander systems in order to unveil the cellular and molecular mechanisms underlying organ regeneration, determine how phylogenetic changes affect regenerative potential, and probe the links between regeneration and ageing.We employ two genetically-tractable salamander models, the axolotl (Ambystoma mexicanum) and the Iberian ribbed newt (Pleurodeles waltl), known for their extreme regenerative abilities and negligible senescence traits.Combining state-of-the-art genetics, cell and molecular biology approaches, advanced imaging, multiomics and cross-species comparative studies, we aim to uncover fundamental principles of regeneration and ageing towards basic and therapeutic applications.Further information can be found at
We offer an
international, creative, science-driven and inspiring environment.The
successful candidates will benefit from our large network of collaborations (
Open Positions
Lab Manager
We are seeking a skilled scientist to manage our newly established laboratory.
Main Responsibilities
a.Order equipment, reagents and lab consumables.
b.Maintain lab stocks and records.
c.Maintain general lab equipment and organisation.
d.Train new staff on common lab techniques and equipment.
e.Assist with animal protocols and licenses.
f.Perform basic molecular/cell biology, image acquisition and data analysis.
g.Conduct research collaboratively as well as independently.
Qualifications
Candidates will have a degree in Molecular Biology, Biochemistry or related subject, experience with general lab management and a strong background on molecular biology approaches including cloning, gene editing, cell culture, microscopy (e.g.confocal, stereo-fluorescence and/or light sheet), tissue processing including preparation, sectioning and staining techniques (e.g.immunostainings IHC/IF and standard/HCR in situ hybridization).Experience in animal research and transgenesis is desirable.Soft skills include outstanding organisational skills, keen attention to details and fluency in spoken and written English.
Molecular Biology Technician
We are seeking a highly skilled Molecular Biologist to join our efforts to unravelling the links between regeneration and ageing.He/she will conduct research collaboratively as well as independently.
Qualifications
The successful candidate will have a strong background on molecular biology approaches including state-of-the-art gene editing, cloning methods, CRISPR/Cas-9 technologies, mTol2 or equivalent systems, animal transgenesis, cell culture, tissue processing including preparation, sectioning and staining techniques (immunostainings IHC/IF and standard/HCR in situ hybridization).Prior experience with regeneration models and/or surgical procedures is a bonus.Soft skills include keen attention to details and fluency in spoken and written English.
Bioinformatician
We are seeking a highly motivated bioinformatician to join our efforts to unravelling the links between regeneration and ageing.
Main Responsibilities
a.Design and conduct bioinformatic analyses of data at single cell and bulk level, including transcriptomic, epigenetic (e.g.DNAm arrays, genomic data) and proteomic datasets, including mRNA sequencing data generated via the 10XMultiome workflow and Illumina sequencing.
b.Conduct cross-species single cell analyses.
c.Analyse and interpret spatial transcriptomics.
d.Contribute to hypothesis generation, experimental design, analytical pipeline documentation, research presentations and manuscript preparation.
e.Provide training/guidance to other team members.
f.Balance independent work and team collaboration.
Qualifications
Candidates should have a degree in bioinformatics or a related field, strong theoretical knowledge and experience in bioinformatics, particularly single cell data and spatial transcriptomics analyses.Fluency in spoken and written English is required.Prior experience in the fields of Regeneration, Aging or Evolutionary biology is a bonus.
Postdoctoral Researcher
We are seeking outstanding, highly motivated postdoctoral researchers to join our efforts to unravelling the links between regeneration and ageing.
Qualifications
Candidates should have a Ph.D.degree in Biology, Biochemistry, Computational Biology or related, an outstanding academic track record, and fluency in spoken and written English.A strong background and research experience in Regenerative, Ageing, Developmental or Evolutionary Biology is desirable.Ideally, candidates would be trained in animal experimentation (not exclusive), tissue culture, bioinformatics and cell/molecular biology techniques.
Welfare Treatment
a.Competitive salary based on the job applicant's work experience and abilities (salary negotiable).
b.Social insurance, paid annual leave, physical examination and supplementary medical insurance, etc.
c.Opportunities for career development and available professional guidance.
How to apply
Please send a resume, a brief summary of research interests & key accomplishments, the names and contacts of 3 referees and other materials demonstrating research capabilities to max.yun@cimrbj.ac.cn, and indicate the applicant's name and specific job position in the email subject.
Contact person: Max H.Yun
This recruitment is valid for the long term until a suitable candidate is recruited.
信息來源于網(wǎng)絡(luò)，如有變更請以原發(fā)布者為準(zhǔn)。
來源鏈接：
https://mp.weixin.qq.com/s/vdRE-eK_pymK5sW3I3Q_Ug
更多最新博士后招收資訊請關(guān)注：
【
【
